Spontaneous Cardiomyopathy in Young Sprague-Dawley Rats
نویسندگان
چکیده
منابع مشابه
Spontaneous neoplastic lesions in aged Sprague-Dawley rats.
Neoplastic lesions were observed in untreated aged Sprague Dawley (SD) rats throughout their lifespan starting at 5 weeks. Their mean survival times were 89 to 105 weeks of age. The total tumor incidences were 70 to 76.7% and 87 to 95.8% in males and females, respectively. The common neoplasmas were pituitary adenoma and adrenal pheochromocytoma in both sexes, testicular Leydig cell tumor in ma...
متن کاملSpontaneous tumors in Sprague-Dawley rats and Swiss mice.
A spontaneous tumor incidence of 45% was noted in 360 Sprague-Dawley rats (179 males and 181 females) and a 26% incidence was seen in 254 Swiss mice (101 males and 153 females) used as untreated control animals in an 18month series of carcinogenesis experiments. The percentage of female rats with tumors was almost double that of males, which difference was accounted for chiefly by the high inci...
متن کاملSpontaneous Tumors in Sprague-Dawley Rats and Swiss Mice1
A spontaneous tumor incidence of 45% was noted in 360 Sprague-Dawley rats (179 males and 181 females) and a 26% incidence was seen in 254 Swiss mice (101 males and 153 females) used as untreated control animals in an 18month series of carcinogenesis experiments. The percentage of female rats with tumors was almost double that of males, which difference was accounted for chiefly by the high inci...
متن کاملNatural Occurrence of Neoplastic Lesions in Young Sprague-Dawley Rats
It is important for the assessment of toxicological effects of chemicals to know what kinds of neoplasms naturally occur in the early life of experimental animals. In the present study, we demonstrated spontaneous neoplasms in Sprague-Dawley rats used in 4-, 13- and 26-week toxicity studies conducted at Bozo Research Center in the last decade. The tumors, which were first observed in 19-week-ol...
متن کاملSpontaneous Histiocytic Sarcoma of the Popliteal Lymph Node in a Young Sprague-Dawley Rat
The present report describes a rare case of spontaneous primary histiocytic sarcoma of the popliteal lymph node in a 19-week-old female Sprague-Dawley (SD) rat. At necropsy, a 10 mm-diameter whitish nodule was found at the site of the femoral muscle in the right hindlimb. Histopathologically, the nodule comprised large pleomorphic histiocyte-like cells with abundant eosinophilic or foamy cytopl...
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ژورنال
عنوان ژورنال: Toxicologic Pathology
سال: 2013
ISSN: 0192-6233,1533-1601
DOI: 10.1177/0192623313478692